This sample shows how to instruct a PDF viewer to display the pages in two columns, with odd-numbered pages on the left.

You can setup desired page layout using PdfDocument.PageLayout property.

C#
using System.Diagnostics;

namespace BitMiracle.Docotic.Pdf.Samples
{
    public static class PageLayout
    {
        public static void Main()
        {
            // NOTE: 
            // When used in trial mode, the library imposes some restrictions.
            // Please visit http://bitmiracle.com/pdf-library/trial-restrictions.aspx
            // for more information.

            string pathToFile = "PageLayout.pdf";

            using (PdfDocument pdf = new PdfDocument("Sample data/jfif3.pdf"))
            {
                pdf.PageLayout = PdfPageLayout.TwoColumnLeft;

                pdf.Save(pathToFile);
            }

            Process.Start(pathToFile);
        }
    }
}
VB
Imports System.Diagnostics

Imports BitMiracle.Docotic.Pdf

Namespace BitMiracle.Docotic.Pdf.Samples
    Public NotInheritable Class PageLayout
        Public Shared Sub Main()
            ' NOTE: 
            ' When used in trial mode, the library imposes some restrictions.
            ' Please visit http://bitmiracle.com/pdf-library/trial-restrictions.aspx
            ' for more information.

            Dim pathToFile As String = "PageLayout.pdf"

            Using pdf As New PdfDocument("Sample data/jfif3.pdf")
                pdf.PageLayout = PdfPageLayout.TwoColumnLeft

                pdf.Save(pathToFile)
            End Using

            Process.Start(pathToFile)
        End Sub
    End Class
End Namespace